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Nicotinamide Inhibits the Lysosomal Cathepsin b-like Protease and Kills African Trypanosomes
Nicotinamide, a soluble compound of the vitamin B(3) group, has antimicrobial activity against several microorganisms ranging from viruses to parasite protozoans. However, the mode of action of this antimicrobial activity is unknown. Here, we investigate the trypanocidal activity of nicotinamide on...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3624436/ https://ncbi.nlm.nih.gov/pubmed/23443665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.449207 |
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