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Retinoic Acid Receptor β Stimulates Hepatic Induction of Fibroblast Growth Factor 21 to Promote Fatty Acid Oxidation and Control Whole-body Energy Homeostasis in Mice

Activation of retinoic acid receptor (RAR) with all-trans-retinoic acid (RA) ameliorates glucose intolerance and insulin resistance in obese mice. The recently discovered fibroblast growth factor 21 (FGF21) is a hepatocyte-derived hormone that restores glucose and lipid homeostasis in obesity-induce...

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Detalhes bibliográficos
Main Authors: Li, Yu, Wong, Kimberly, Walsh, Kenneth, Gao, Bin, Zang, Mengwei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624431/
https://ncbi.nlm.nih.gov/pubmed/23430257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.429852
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