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Constitutive Internalization of the Leucine-rich G Protein-coupled Receptor-5 (LGR5) to the Trans-Golgi Network

LGR5 is a Wnt pathway associated G protein-coupled receptor (GPCR) that serves as a molecular determinant of stem cells in numerous tissues including the intestine, stomach, hair follicle, eye, and mammary gland. Despite its importance as a marker for this critical niche, little is known about LGR5...

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Detalhes bibliográficos
Main Authors: Snyder, Joshua C., Rochelle, Lauren K., Lyerly, H. Kim, Caron, Marc G., Barak, Lawrence S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624412/
https://ncbi.nlm.nih.gov/pubmed/23439653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.447540
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