Infection of the Upper Respiratory Tract with Seasonal Influenza A(H3N2) Virus Induces Protective Immunity in Ferrets against Infection with A(H1N1)pdm09 Virus after Intranasal, but Not Intratracheal, Inoculation

The clinical symptoms caused by infection with influenza A virus vary widely and depend on the strain causing the infection, the dose and route of inoculation, and the presence of preexisting immunity. In most cases, seasonal influenza A viruses cause relatively mild upper respiratory tract disease,...

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Autori principali: Bodewes, Rogier, Kreijtz, Joost H. C. M., van Amerongen, Geert, Hillaire, Marine L. B., Vogelzang-van Trierum, Stella E., Nieuwkoop, Nella J., van Run, Peter, Kuiken, Thijs, Fouchier, Ron A. M., Osterhaus, Albert D. M. E., Rimmelzwaan, Guus F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624397/
https://ncbi.nlm.nih.gov/pubmed/23365444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02536-12
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