Antibody-Dependent, FcγRI-Mediated Neutralization of HIV-1 in TZM-bl Cells Occurs Independently of Phagocytosis

We previously showed that expression of human FcγRI on TZM-bl cells potentiates neutralization by gp41 membrane-proximal external region (MPER)-specific antibodies. Here we show that lysosomotropic reagents known to block phagocytosis do not diminish this effect. We also show that FcγRI occasionally...

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Detaylı Bibliyografya
Asıl Yazarlar: Perez, Lautaro G., Zolla-Pazner, Susan, Montefiori, David C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Pathogenesis and Immunity
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624318/
https://ncbi.nlm.nih.gov/pubmed/23408628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00278-13
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