Robust Immunity to an Auxotrophic Mycobacterium bovis BCG-VLP Prime-Boost HIV Vaccine Candidate in a Nonhuman Primate Model

We previously reported that a recombinant pantothenate auxotroph of Mycobacterium bovis BCG expressing human immunodeficiency virus type 1 (HIV-1) subtype C Gag (rBCGpan-Gag) efficiently primes the mouse immune system for a boost with a recombinant modified vaccinia virus Ankara (rMVA) vaccine. In t...

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Détails bibliographiques
Auteurs principaux: Chege, Gerald K., Burgers, Wendy A., Stutz, Helen, Meyers, Ann E., Chapman, Rosamund, Kiravu, Agano, Bunjun, Rubina, Shephard, Enid G., Jacobs, William R., Rybicki, Edward P., Williamson, Anna-Lise
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624307/
https://ncbi.nlm.nih.gov/pubmed/23449790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03178-12
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