Short-Chain Fatty Acids Stimulate Angiopoietin-Like 4 Synthesis in Human Colon Adenocarcinoma Cells by Activating Peroxisome Proliferator-Activated Receptor γ

Angiopoietin-like protein 4 (ANGPTL4/FIAF) has been proposed as a circulating mediator between the gut microbiota and fat storage. Here, we show that transcription and secretion of ANGPTL4 in human T84 and HT29 colon adenocarcinoma cells is highly induced by physiological concentrations of short-cha...

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Main Authors: Alex, Sheril, Lange, Katja, Amolo, Tom, Grinstead, Jeffrey S., Haakonsson, Anders K., Szalowska, Ewa, Koppen, Arjen, Mudde, Karin, Haenen, Daniëlle, Al-Lahham, Sa'ad, Roelofsen, Han, Houtman, René, van der Burg, Bart, Mandrup, Susanne, Bonvin, Alexandre M. J. J., Kalkhoven, Eric, Müller, Michael, Hooiveld, Guido J., Kersten, Sander
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624264/
https://ncbi.nlm.nih.gov/pubmed/23339868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00858-12
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