Alphaherpesviral US3 Kinase Induces Cofilin Dephosphorylation To Reorganize the Actin Cytoskeleton

The conserved alphaherpesviral serine/threonine kinase US3 causes dramatic actin rearrangements, associated with increased viral spread. Here, we show that US3 of pseudorabies virus (PRV) leads to activation (dephosphorylation) of the central actin regulator cofilin. A mutation that impairs US3 kina...

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Detaylı Bibliyografya
Asıl Yazarlar: Jacob, Thary, Van den Broeke, Céline, van Troys, Marleen, Waterschoot, Davy, Ampe, Christophe, Favoreel, Herman W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2013
Konular:
Virus-Cell Interactions
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624233/
https://ncbi.nlm.nih.gov/pubmed/23365433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03107-12
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