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The BCL11A Transcription Factor Directly Activates RAG Gene Expression and V(D)J Recombination
Recombination-activating gene 1 protein (RAG1) and RAG2 are critical enzymes for initiating variable-diversity-joining (VDJ) segment recombination, an essential process for antigen receptor expression and lymphocyte development. The transcription factor BCL11A is required for B cell development, but...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3624176/ https://ncbi.nlm.nih.gov/pubmed/23438597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00987-12 |
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