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Characterization of a membrane-active anti-tumor agent, UA8967
Deletions or mutations in the tumor suppressor gene DPC4 (deleted in pancreatic carcinoma locus 4) are common in colon and pancreatic cancers. Using the Target-related Affinity Profiling (TRAP) chemical library screening method, a novel agent, UA8967, was selected for further studies because it show...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3624034/ https://ncbi.nlm.nih.gov/pubmed/23179338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-012-9901-z |
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