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Adult female wildtype, but not oestrogen receptor β knockout, mice have decreased depression-like behaviour during pro-oestrus and following administration of oestradiol or diarylpropionitrile

Studies in people and animal models suggest that depression is influenced by natural, fluctuations in the levels of 17β-oestradiol (E(2)), as well as administration of E(2)-based therapies, such as selective oestrogen receptor modulators (SERMs). Elucidating the effects and mechanisms of E(2) is imp...

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Библиографические подробности
Главные авторы: Walf, AA, Koonce, CJ, Frye, CA
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623951/
https://ncbi.nlm.nih.gov/pubmed/18562442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881108089598
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