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Adult female wildtype, but not oestrogen receptor β knockout, mice have decreased depression-like behaviour during pro-oestrus and following administration of oestradiol or diarylpropionitrile
Studies in people and animal models suggest that depression is influenced by natural, fluctuations in the levels of 17β-oestradiol (E(2)), as well as administration of E(2)-based therapies, such as selective oestrogen receptor modulators (SERMs). Elucidating the effects and mechanisms of E(2) is imp...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623951/ https://ncbi.nlm.nih.gov/pubmed/18562442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881108089598 |
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