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The hCMEC/D3 cell line as a model of the human blood brain barrier

Since the first attempts in the 1970s to isolate cerebral microvessel endothelial cells (CECs) in order to model the blood–brain barrier (BBB) in vitro, the need for a human BBB model that closely mimics the in vivo phenotype and is reproducible and easy to grow, has been widely recognized by cerebr...

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Detalhes bibliográficos
Main Authors: Weksler, Babette, Romero, Ignacio A, Couraud, Pierre-Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623852/
https://ncbi.nlm.nih.gov/pubmed/23531482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-10-16
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