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Functional expression of a proton-coupled organic cation (H(+)/OC) antiporter in human brain capillary endothelial cell line hCMEC/D3, a human blood–brain barrier model

BACKGROUND: Knowledge of the molecular basis and transport function of the human blood–brain barrier (BBB) is important for not only understanding human cerebral physiology, but also development of new central nervous system (CNS)-acting drugs. However, few studies have been done using human brain c...

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Detalhes bibliográficos
Main Authors: Shimomura, Keita, Okura, Takashi, Kato, Sayaka, Couraud, Pierre-Olivier, Schermann, Jean-Michel, Terasaki, Tetsuya, Deguchi, Yoshiharu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3564923/
https://ncbi.nlm.nih.gov/pubmed/23351963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-10-8
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