Correlation of Notch1, pAKT and nuclear NF-κB expression in triple negative breast cancer

Gene expression profiling reveals elevated Notch1 mRNA expression in triple negative breast cancers (TNBC), both basaloid and claudin-low subtypes. Notch ligands, Jagged1 and Jagged2, have been correlated with poor prognosis in TNBC. AKT, an oncogenic protein kinase family that is activated downstre...

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Main Authors: Zhu, He, Bhaijee, Feriyl, Ishaq, Nivin, Pepper, Dominique J, Backus, Kandis, Brown, Alexandra S, Zhou, Xinchun, Miele, Lucio
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2013
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623841/
https://ncbi.nlm.nih.gov/pubmed/23593544
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