AKT and 14-3-3 Regulate Notch4 Nuclear Localization

Members of the Notch family of transmembrane receptors, Notch1-4 in mammals, are involved in the regulation of cell fate decisions and cell proliferation in various organisms. The Notch4 isoform, which is specific to mammals, was originally identified as a viral oncogene in mice, Int3, able to initi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ramakrishnan, Gopalakrishnan, Davaakhuu, Gantulga, Chung, Wen Cheng, Zhu, He, Rana, Ajay, Filipovic, Aleksandra, Green, Andrew R., Atfi, Azeddine, Pannuti, Antonio, Miele, Lucio, Tzivion, Guri
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350099/
https://ncbi.nlm.nih.gov/pubmed/25740432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08782
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