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Npc1 Acting in Neurons and Glia Is Essential for the Formation and Maintenance of CNS Myelin

Cholesterol availability is rate-limiting for myelination, and prior studies have established the importance of cholesterol synthesis by oligodendrocytes for normal CNS myelination. However, the contribution of cholesterol uptake through the endocytic pathway has not been fully explored. To address...

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Hlavní autoři: Yu, Ting, Lieberman, Andrew P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623760/
https://ncbi.nlm.nih.gov/pubmed/23593041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003462
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