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Shining a Light on Dark Sequencing: Characterising Errors in Ion Torrent PGM Data
The Ion Torrent Personal Genome Machine (PGM) is a new sequencing platform that substantially differs from other sequencing technologies by measuring pH rather than light to detect polymerisation events. Using re-sequencing datasets, we comprehensively characterise the biases and errors introduced b...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623719/ https://ncbi.nlm.nih.gov/pubmed/23592973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003031 |
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