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Shining a Light on Dark Sequencing: Characterising Errors in Ion Torrent PGM Data

The Ion Torrent Personal Genome Machine (PGM) is a new sequencing platform that substantially differs from other sequencing technologies by measuring pH rather than light to detect polymerisation events. Using re-sequencing datasets, we comprehensively characterise the biases and errors introduced b...

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Bibliografische gegevens
Hoofdauteurs: Bragg, Lauren M., Stone, Glenn, Butler, Margaret K., Hugenholtz, Philip, Tyson, Gene W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623719/
https://ncbi.nlm.nih.gov/pubmed/23592973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003031
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