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Improving Indel Detection Specificity of the Ion Torrent PGM Benchtop Sequencer

The emergence of benchtop sequencers has made clinical genetic testing using next-generation sequencing more feasible. Ion Torrent's PGM(TM) is one such benchtop sequencer that shows clinical promise in detecting single nucleotide variations (SNVs) and microindel variations (indels). However, t...

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Hlavní autoři: Yeo, Zhen Xuan, Chan, Maurice, Yap, Yoon Sim, Ang, Peter, Rozen, Steve, Lee, Ann Siew Gek
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446914/
https://ncbi.nlm.nih.gov/pubmed/23029247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045798
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