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Risk Assessment, Genetic Testing and Management of Lynch Syndrome

Of the estimated 150,000 colorectal cancer (CRC) cases diagnosed annually, approximately 30% have a familial basis and 3–5% are due to high penetrance inherited cancer syndromes. Lynch syndrome or hereditary non polyposis colorectal cancer (HNPCC), caused by inherited germline mutations in mismatch...

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Bibliografische gegevens
Hoofdauteurs: Grover, Shilpa, Syngal, Sapna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623693/
https://ncbi.nlm.nih.gov/pubmed/20064292
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