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Risk Assessment, Genetic Testing and Management of Lynch Syndrome
Of the estimated 150,000 colorectal cancer (CRC) cases diagnosed annually, approximately 30% have a familial basis and 3–5% are due to high penetrance inherited cancer syndromes. Lynch syndrome or hereditary non polyposis colorectal cancer (HNPCC), caused by inherited germline mutations in mismatch...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623693/ https://ncbi.nlm.nih.gov/pubmed/20064292 |
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