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Inactivation of Caenorhabditis elegans aminopeptidase DNPP-1 restores endocytic sorting and recycling in tat-1 mutants

In Caenorhabditis elegans, the P4-ATPase TAT-1 and its chaperone, the Cdc50 family protein CHAT-1, maintain membrane phosphatidylserine (PS) asymmetry, which is required for membrane tubulation during endocytic sorting and recycling. Loss of tat-1 and chat-1 disrupts endocytic sorting, leading to de...

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Hlavní autoři: Li, Xin, Chen, Baohui, Yoshina, Sawako, Cai, Tanxi, Yang, Fuquan, Mitani, Shohei, Wang, Xiaochen
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623637/
https://ncbi.nlm.nih.gov/pubmed/23427264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-10-0730
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