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Radiosynthesis and preclinical evaluation of [(11)C]prucalopride as a potential agonist PET ligand for the 5-HT(4) receptor
BACKGROUND: Serotonin 5-HT(4) receptor (5-HT(4)-R) agonists are potential therapeutic agents for enterokinetic and cognitive disorders and are marketed for treatment of constipation. The aim of this study was to develop an agonist positron emission tomography (PET) ligand in order to label the activ...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623622/ https://ncbi.nlm.nih.gov/pubmed/23557209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-219X-3-24 |
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