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Structural differences between repressed and derepressed forms of p60c-src.

The kinase activity of p60c-src is derepressed by removal of phosphate from Tyr-527, mutation of this residue to Phe, or binding of a carboxy-terminal antibody. We have compared the structures of repressed and active p60c-src, using proteases. All forms of p60c-src are susceptible to proteolysis at...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Main Authors: MacAuley, A, Cooper, J A
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 1989
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362337/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2474758/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.6.2648
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