Structural differences between repressed and derepressed forms of p60c-src.
The kinase activity of p60c-src is derepressed by removal of phosphate from Tyr-527, mutation of this residue to Phe, or binding of a carboxy-terminal antibody. We have compared the structures of repressed and active p60c-src, using proteases. All forms of p60c-src are susceptible to proteolysis at...
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| Udgivet i: | Mol Cell Biol |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
1989
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362337/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2474758/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.6.2648-2656.1989 |
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