A carregar...
A Novel Mechanism Underlies the Hepatotoxicity of Pyrazinamide
Relatively little is known about the hepatotoxicity of pyrazinamide (PZA). PZA requires activation by amidase to form pyrazinoic acid (PA). Xanthine oxidase then hydroxylates PA to form 5-hydroxypyrazinoic acid (5-OH-PA). PZA can also be directly oxidized to form 5-OH-PZA. Before this study, it was...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623344/ https://ncbi.nlm.nih.gov/pubmed/23357778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01866-12 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|