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Clinical and Toxicodynamic Evidence that High-Dose Pyrazinamide Is Not More Hepatotoxic than the Low Doses Currently Used

Antimicrobial pharmacokinetic-pharmacodynamic studies suggest that pyrazinamide doses higher than those currently recommended may be more efficacious. However, high pyrazinamide doses are believed to be hepatotoxic. Searches for clinical trials in MEDLINE, EBSCOHOST, and the Cochrane Controlled Tria...

Deskribapen osoa

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Xehetasun bibliografikoak
Egile Nagusiak: Pasipanodya, Jotam G., Gumbo, Tawanda
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897291/
https://ncbi.nlm.nih.gov/pubmed/20439617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01567-09
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