Pharmacodynamics and Dose-Response Relationships of Liposomal Amphotericin B against Different Azole-Resistant Aspergillus fumigatus Isolates in a Murine Model of Disseminated Aspergillosis

The management of invasive aspergillosis (IA) has become more complicated due to the emergence of acquired azole resistance in Aspergillus fumigatus, which is associated with treatment failure and a mortality rate of 88%. Treatment with liposomal amphotericin B (L-AmB) may be a useful alternative to...

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Главные авторы: Seyedmousavi, Seyedmojtaba, Melchers, Willem J. G., Mouton, Johan W., Verweij, Paul E.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2013
Предметы:
Experimental Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623333/
https://ncbi.nlm.nih.gov/pubmed/23380732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02226-12
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