Inhibitory and Fungicidal Effects of Antifungal Drugs against Aspergillus Species in the Presence of Serum

Given the high protein binding rates of antifungal drugs and the effect of serum proteins on Aspergillus growth, we investigated the in vitro pharmacodynamics of amphotericin B, voriconazole, and three echinocandins in the presence of human serum, assessing both inhibitory and fungicidal effects. In...

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Main Authors: Elefanti, Antigoni, Mouton, Johan W., Krompa, Katerina, Al-Saigh, Rafal, Verweij, Paul E., Zerva, Loukia, Meletiadis, Joseph
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Susceptibility
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623331/
https://ncbi.nlm.nih.gov/pubmed/23318807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01573-12
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