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AZD5438, an Inhibitor of Cdk1, 2, and 9, Enhances the Radiosensitivity of Non-Small Cell Lung Carcinoma Cells

PURPOSE: Radiation therapy (RT) is one of the primary modalities for treatment of non-small cell lung cancer (NSCLC). However, due to the intrinsic radiation resistance of these tumors, many patients experience RT failure, which leads to considerable tumor progression including regional lymph node a...

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Detalhes bibliográficos
Main Authors: Raghavan, Pavithra, Tumati, Vasu, Yu, Lan, Chan, Norman, Tomimatsu, Nozomi, Burma, Sandeep, Bristow, Robert G., Saha, Debabrata
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623267/
https://ncbi.nlm.nih.gov/pubmed/22795803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2012.05.035
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