Regulation of mouse CYP1A1 gene expression by dioxin: requirement of two cis-acting elements during induction.

The mouse cytochrome P1450 (CYP1A1) gene is responsible for the metabolism of numerous carcinogens and toxic chemicals. Induction by the environmental contaminant tetrachlorodibenzo-p-dioxin (TCDD) requires a functional aromatic hydrocarbon (Ah) receptor. We examined the 5'-flanking region of the CY...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Neuhold, L A, Shirayoshi, Y, Ozato, K, Jones, J E, Nebert, D W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362311/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2548080/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.6.2378-2386.1989
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