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GABA(B) receptor subtypes differentially modulate synaptic inhibition in the dentate gyrus to enhance granule cell output

BACKGROUND AND PURPOSE: Activation of GABA(B) receptors in the dentate gyrus (DG) enhances granule cell (GC) activity by reducing synaptic inhibition imposed by hilar interneurons. This disinhibitory action facilitates signal transfer from the perforant path to the hippocampus. However, as the two m...

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Detalhes bibliográficos
Main Authors: Foster, Joshua D, Kitchen, Ian, Bettler, Bernhard, Chen, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623052/
https://ncbi.nlm.nih.gov/pubmed/23186302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12073
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