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GABA(B) receptor subtypes differentially modulate synaptic inhibition in the dentate gyrus to enhance granule cell output
BACKGROUND AND PURPOSE: Activation of GABA(B) receptors in the dentate gyrus (DG) enhances granule cell (GC) activity by reducing synaptic inhibition imposed by hilar interneurons. This disinhibitory action facilitates signal transfer from the perforant path to the hippocampus. However, as the two m...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623052/ https://ncbi.nlm.nih.gov/pubmed/23186302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12073 |
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