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Oral resveratrol therapy inhibits cancer-induced skeletal muscle and cardiac atrophy in vivo

The mechanism by which cancer mediates muscle atrophy has been delineated in the past 3 decades, and includes a prominent role of tumor-derived cytokines, such as IL-6, TNFα and IL-1. These cytokines interact with their cognate receptors on muscle to activate the downstream transcription factor NF-κ...

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Detalhes bibliográficos
Main Authors: Shadfar, Scott, Couch, Marion E., McKinney, Kibwei A., Weinstein, Lisa J., Yin, Xiaoying, Rodríguez, Jessica E., Guttridge, Denis C., Willis, Monte
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623008/
https://ncbi.nlm.nih.gov/pubmed/21660860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01635581.2011.563032
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