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Metabolic derangements in the gastrocnemius and the effect of Compound A therapy in a murine model of cancer cachexia

BACKGROUND: Cancer cachexia is a severe wasting syndrome characterized by the progressive loss of lean body mass and systemic inflammation. Inhibiting the signaling of the transcription factor nuclear factor kappa B (NF-κB) largely prevents cancer-induced muscle wasting in murine models. We have pre...

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Main Authors: Der-Torossian, Hirak, Wysong, Ashley, Shadfar, Scott, Willis, Monte S., McDunn, Jonathan, Couch, Marion E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684703/
https://ncbi.nlm.nih.gov/pubmed/23344889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13539-012-0101-7
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