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Cooperativity of sequence elements mediates tissue specificity of the rat insulin II gene.
The 5'-flanking region of the rat insulin II gene (-448 to +50) is sufficient for tissue-specific expression. To further determine the tissue-specific cis-acting element(s), important sequences defined by linker-scanning mutagenesis were placed upstream of a heterologous promoter and transfecte...
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| Publicado no: | Mol Cell Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362286/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2181285/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.4.1784 |
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