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Cooperativity of sequence elements mediates tissue specificity of the rat insulin II gene.

The 5'-flanking region of the rat insulin II gene (-448 to +50) is sufficient for tissue-specific expression. To further determine the tissue-specific cis-acting element(s), important sequences defined by linker-scanning mutagenesis were placed upstream of a heterologous promoter and transfecte...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hwung, Y P, Gu, Y Z, Tsai, M J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC362286/
https://ncbi.nlm.nih.gov/pubmed/2181285
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