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Interferon-induced ISG15 pathway: an ongoing virus–host battle

ISG15 is an interferon (IFN)-induced ubiquitin-like protein that is conjugated to target proteins via the sequential action of three enzymes that are also induced by IFN. Unlike ubiquitin, which is highly conserved, the sequence of ISG15 varies between species. ISG15 conjugation inhibits many viruse...

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Detalles Bibliográficos
Main Authors: Zhao, Chen, Collins, Mark N., Hsiang, Tien-Ying, Krug, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Ltd. 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622817/
https://ncbi.nlm.nih.gov/pubmed/23414970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2013.01.005
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