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Increased Susceptibility of Natural Killer T cell Deficient Mice to Acetaminophen-Induced Liver injury

Acetaminophen (APAP) overdose causes severe and fulminant liver injuries. The underlying mechanism of APAP-induced liver injury (AILI), studied by a murine model, displays similar characteristics of injury as those seen in patients. Previous studies suggest that aside from APAP-induced direct damage...

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Detalhes bibliográficos
Main Authors: Martin-Murphy, Brittany V., Kominsky, Douglas J., Orlicky, David J., Donohue, Terrence M., Ju, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622784/
https://ncbi.nlm.nih.gov/pubmed/23150232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26134
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