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FOXP3: Genetic and Epigenetic Implications for Autoimmunity
FOXP3 plays an essential role in the maintenance of self-tolerance and, thus, in preventing autoimmune diseases. Inactivating mutations of FOXP3 cause immunodysregulation, polyendocrinopathy, and enteropathy, X-linked syndrome. FOXP3-expressing regulatory T cells attenuate autoimmunity as well as im...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3622774/ https://ncbi.nlm.nih.gov/pubmed/23313429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2012.12.004 |
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