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RKIP Regulates MAP Kinase Signaling in Cells with Defective B-Raf Activity

MAP kinase (MAPK) signaling results from activation of Raf kinases in response to external or internal stimuli. Here, we demonstrate that Raf Kinase Inhibitory Protein (RKIP) regulates the activation of MAPK when B-Raf signaling is defective. We used multiple models including mouse embryonic fibrobl...

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書誌詳細
主要な著者: Zeng, Lingchun, Ehrenreiter, Karin, Menon, Jyotsana, Menard, Ray, Kern, Florian, Nakazawa, Yoko, Bevilacqua, Elena, Imamoto, Akira, Baccarini, Manuela, Rosner, Marsha Rich
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622756/
https://ncbi.nlm.nih.gov/pubmed/23416466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.02.005
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