RKIP Regulates MAP Kinase Signaling in Cells with Defective B-Raf Activity

MAP kinase (MAPK) signaling results from activation of Raf kinases in response to external or internal stimuli. Here, we demonstrate that Raf Kinase Inhibitory Protein (RKIP) regulates the activation of MAPK when B-Raf signaling is defective. We used multiple models including mouse embryonic fibrobl...

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Bibliografski detalji
Glavni autori: Zeng, Lingchun, Ehrenreiter, Karin, Menon, Jyotsana, Menard, Ray, Kern, Florian, Nakazawa, Yoko, Bevilacqua, Elena, Imamoto, Akira, Baccarini, Manuela, Rosner, Marsha Rich
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622756/
https://ncbi.nlm.nih.gov/pubmed/23416466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.02.005
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