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Loss of p53 in Stromal Fibroblasts Promotes Epithelial Cell Invasion through Redox-Mediated ICAM1 Signal

Tumor microenvironment plays a major role in cancer development. Understanding how the stroma affects epithelial transformation will provide a basis for new preventive strategies. Recent evidences suggest that oxidative stress in stroma may play a role in cancer progression and loss of p53 function...

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Detalhes bibliográficos
Main Authors: Trachootham, Dunyaporn, Chen, Gang, Zhang, Wan, Lu, Weiqin, Zhang, Hui, Liu, Jinsong, Huang, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622735/
https://ncbi.nlm.nih.gov/pubmed/23376231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.01.011
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