Ligand-induced phosphorylation of the colony-stimulating factor 1 receptor can occur through an intermolecular reaction that triggers receptor down modulation.

Eitemau Tebyg

• Ligand and protein kinase C downmodulate the colony-stimulating factor 1 receptor by independent mechanisms.
  gan: Downing, J R, et al.
  Cyhoeddwyd: (1989)
• Ligand-induced tyrosine kinase activity of the colony-stimulating factor 1 receptor in a murine macrophage cell line.
  gan: Downing, J R, et al.
  Cyhoeddwyd: (1988)
• Structural features of the colony-stimulating factor 1 receptor that affect its association with phosphatidylinositol 3-kinase.
  gan: Shurtleff, S A, et al.
  Cyhoeddwyd: (1990)
• Peptide antisera to human colony-stimulating factor 1 receptor detect ligand-induced conformational changes and a binding site for phosphatidylinositol 3-kinase.
  gan: Downing, J R, et al.
  Cyhoeddwyd: (1991)
• A point mutation at tyrosine-809 in the human colony-stimulating factor 1 receptor impairs mitogenesis without abrogating tyrosine kinase activity, association with phosphatidylinositol 3-kinase, or induction of c-fos and junB genes.
  gan: Roussel, M F, et al.
  Cyhoeddwyd: (1990)