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Ligand-induced phosphorylation of the colony-stimulating factor 1 receptor can occur through an intermolecular reaction that triggers receptor down modulation.

Ligand-induced tyrosine phosphorylation of the human colony-stimulating factor 1 receptor (CSF-1R) could involve either an intra- or intermolecular mechanism. We therefore examined the ability of a CSF-1R carboxy-terminal truncation mutant to phosphorylate a kinase-defective receptor, CSF-1R[met 616...

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Udgivet i:Mol Cell Biol
Principais autores: Ohtsuka, M, Roussel, M F, Sherr, C J, Downing, J R
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362271/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2157138/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.10.4.1664-1671.1990
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