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Attenuation of Nonsense-Mediated mRNA Decay Enhances In Vivo Nonsense Suppression
Nonsense suppression therapy is an approach to treat genetic diseases caused by nonsense mutations. This therapeutic strategy pharmacologically suppresses translation termination at Premature Termination Codons (PTCs) in order to restore expression of functional protein. However, the process of Nons...
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Κύριοι συγγραφείς: | , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Public Library of Science
2013
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3622682/ https://ncbi.nlm.nih.gov/pubmed/23593225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060478 |
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