G-Protein Coupled Receptor Family C, Group 5, Member A (GPRC5A) Expression Is Decreased in the Adjacent Field and Normal Bronchial Epithelia of Patients with Chronic Obstructive Pulmonary Disease and Non–Small-Cell Lung Cancer

INTRODUCTION: Understanding oncogenes and tumor suppressor genes expression patterns is essential for characterizing lung cancer pathogenesis. We have previously demonstrated that mGprc5a/hGPRC5A is a lung-specific tumor suppressor evidenced by inflammation-mediated tumorigenesis in Gprc5a-knockout...

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Hlavní autoři: Fujimoto, Junya, Kadara, Humam, Garcia, Melinda M., Kabbout, Mohamed, Behrens, Carmen, Liu, Diane D., Lee, J. Jack, Solis, Luisa M., Kim, Edward S., Kalhor, Neda, Moran, Cesar, Sharafkhaneh, Amir, Lotan, Reuben, Wistuba, Ignacio I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622592/
https://ncbi.nlm.nih.gov/pubmed/23154545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e31826bb1ff
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