Translocation of an erythroid-specific hypersensitive site in deletion-type hereditary persistence of fetal hemoglobin.

Hereditary persistence of fetal hemoglobin (HPFH) can involve large deletions which eliminate the 3' end of the beta-like globin gene cluster and more than 70 kilobases (kb) of flanking DNA. Blot hybridization revealed a DNase I-hypersensitive site extending from 1.1 to 1.4 kb downstream of the...

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Main Authors: Elder, J T, Forrester, W C, Thompson, C, Mager, D, Henthorn, P, Peretz, M, Papayannopoulou, T, Groudine, M
格式: Artigo
語言:Inglês
出版: 1990
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC362240/
https://ncbi.nlm.nih.gov/pubmed/1690839
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