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Bile salt-stimulated phospholipid efflux mediated by ABCB4 localized in nonraft membranes

ABCB4 is necessary for the secretion of phospholipids from hepatocytes into bile and for the protection of cell membranes against bile salts. Lipid rafts are plasma membrane microdomains containing high contents of cholesterol and sphingolipids, which are separated by Triton X-100 extraction or Opti...

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Detalhes bibliográficos
Main Authors: Morita, Shin-ya, Tsuda, Tadanori, Horikami, Manami, Teraoka, Reiko, Kitagawa, Shuji, Terada, Tomohiro
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622319/
https://ncbi.nlm.nih.gov/pubmed/23468132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M032425
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