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Type I interferons: crucial participants in disease amplification in autoimmunity

A significant body of data implicates the type I interferon (IFN) pathway in the pathogenesis of autoimmune rheumatic diseases. In these disorders, a reinforcing cycle of IFN production can contribute to immunopathology through multiple mechanisms. The type I IFN cytokines are pleiotropic in their e...

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Detalhes bibliográficos
Main Authors: Hall, John C., Rosen, Antony
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622245/
https://ncbi.nlm.nih.gov/pubmed/20046205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrrheum.2009.237
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