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Signaling through Purinergic Receptors for ATP Induces Human Cutaneous Innate and Adaptive Th17 Responses: Implications in the Pathogenesis of Psoriasis

Human cutaneous DCs have the ability to prime and bias Th17 lymphocytes. However, the factors that stimulate cutaneous DCs to induce Th17 responses are not well known. Alarmins, such as ATP, likely play a pivotal role in the induction and maintenance of cutaneous immune responses by stimulating DC m...

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Detalhes bibliográficos
Main Authors: Killeen, Meaghan E., Ferris, Laura, Kupetsky, Erine A., Falo, Louis, Mathers, Alicia R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622186/
https://ncbi.nlm.nih.gov/pubmed/23479230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202045
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